A powerful form of vitamin E, called tocotrienols, has been shown to prevent cellular aging. As we age, telomeres shorten with decreased telomerase activity and levels of damaged DNA increase. Telomeres reside at either of the sections of DNA occurring at the ends of a chromosome. Telomeres protect the DNA material inside the chromosomes. The shortening of telomeres during each round of cell division may be part of the natural aging of cells. In this study, researchers reversed the morphology of senescent cells to resemble that of young cells with decreased damaged DNA and telomere length. These findings confirmed the ability of tocotrienol-rich fraction in preventing cellular ageing by restoring telomere length and telomerase activity, reducing damaged DNA, and reversing cell cycle arrest associated with senescence.
